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News Medical on MSNHow olive oil bioactives regulate genes linked to insulin resistanceOlive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...
leading to the downstream phosphorylation of insulin receptor substrate proteins. One of the biggest factors contributing to a variety of brain decline happens due to insulin resistance – which ...
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New enzyme discovery offers hope for millions of diabetes patientsThe SCAN enzyme employs this mechanism, selectively nitrosylating target proteins such as the insulin receptor and its substrates. Interestingly, the researchers discovered elevated SCAN activity ...
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News Medical on MSNA pathway that contributes to insulin resistance can be targeted, mouse study showsThe hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...
Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) acts as a negative regulator of the insulin signaling pathway by dephosphorylating both the insulin receptor (IR) and the insulin receptor ...
Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes.
Dopamine receptors bind dopamine, insulin receptors bind insulin ... and a single protein may in turn be the substrate for multiple kinases and phosphatases. At any one time, a cell is receiving ...
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