Thrombin mediates fibrin polymerization and is known to be involved in acute and chronic inflammatory processes in vivo. Flick et al. have used various genetically engineered mouse models to study ...

A surface protease helps Yersinia pestis plow its way through the body during pneumonic plague. During the 14th through 16th centuries, Y. pestis caused a pandemic of plague that killed a third of ...

In 2023, Roche said it was removing TNKase for stroke from its phase 3 programmes after a readout of the TIMELESS trial, but ...

Genentech’s label expansion for TNKase consolidates its market position for pharmacological stroke treatments.

Fibrinolytic therapy, also known as thrombolytic therapy, is used to lyse acute blood clots by activating plasminogen, resulting in the formation of plasmin, which cleaves the fibrin cross-links ...