Due to an inherited mutation in the ATM (ataxia-telangiectasia mutated) gene, Domitrovits knew that she was at increased risk for breast and other forms of cancer. Just weeks prior, she had completed ...
The ATM gene (mutated in the disease ataxia telangiectasia) activates the p53 tumor suppressor protein in response to DNA damage, explaining the higher incidence of cancer in AT patients.
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